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Clinical Trials

Current clinical trials

Ocular Oncology and Pathology
Pediatric Ophthalmology

Closed clinical trials

Ocular Oncology and Pathology
Pediatric Ophthalmology
Vision Rehabilitation Research

A leader in clinical research

Emory Eye Center is a recently renovated, state-of-the-art facility located in metropolitan Atlanta, Georgia, which has a population estimated at 6 million.

With more than 120,000 patient encounters annually, Emory Eye Center is the largest, most comprehensive eye care facility in Georgia. Our 50 ophthalmologists and optometrists, most of whom are sub-specialty trained, are dedicated to quality patient care, education, teaching and research.

We have successfully pioneered and participated in hundreds of clinical trials and studies including compassionate use, investigator-initiated and Phase I through Phase  IV studies.

We are recognized as a site where sponsors get accurate, timely and meticulous data collection; meet recruitment goals; and maintain excellent study subject retention.

Our Clinical Trials program is led by Medical Director Beau B. Bruce, MD, PhD, a practicing neuro-ophthalmologist with a PhD in epidemiology. With a Master's degree in clinical research, Dr. Bruce has participated as PI for numerous clinical trials, NIH-sponsored and other research and served on the steering and DSMB committees of national and international research projects.

Site capabilities

Emory Eye Center boasts highly experienced, nationally-recognized study coordinators and leaders in ophthalmic photography. Cross-certified for numerous studies, our staff is proficient in the techniques of BCVA assessments and other visual function examinations; ophthalmic photography; anterior and posterior OCT imaging; and ultrasonography.
Research capabilities include:

  • State-of-the-art diagnostic equipment
  • Dedicated, specifically designed, multi-study certified 4-meter exam lanes featuring ETDRS and electronic visual acuity testing with specialized lighting on rheostats to meet any protocol-specific lighting requirements
  • Designated monitoring rooms with high speed internet and phone access
  • A dedicated research administration staff

Our imaging section performs anterior and posterior segment photography/angiography (Topcon Zeiss), anterior and posterior segment OCT (Cirrus, Heidelberg Spectralis ), HRT III, Corneal Topography (Zeiss Atlas, Oculus Pentacam, B&L Orbscan Reichert Ocular Response Analyzer), microperimetry, and diagnostic and biometric ultrasonography (immersion and non-contact A; real-time B and UBM).

The visual field section employs Humphrey, Octopus and Goldmann perimeters and on-site multifocal electrophysiology testing.

Biologic specimens are collected, centrifuged, stored (-20F and -86F freezers), packaged under CLIA accreditation and shipped by EHSO certified personnel. Investigational drugs are managed by Emory's Investigational Drug Service.

Trials and studies

Under the direction of our internationally recognized faculty, we have conducted trials and studies (pharmacologic, device, surgical treatment, registries) in:

  • Cornea Dry eye, herpetic eye disease, keratoconus, contact lenses, cross linking, keratoprosthesis, refractive, IOL
  • Glaucoma Adult and pediatric open angle, ocular hypertension, angle closure
  • Global Ophthalmology Trachoma, river blindness, diabetic retinopathy, cataracts
  • Low Vision/Vision Rehabilitation Vision and functional outcomes, orientation/mobility, specially designed prisms/telescopes, implantable miniature telescope, macular degeneration/cortical plasticity
  • Neuro-Ophthalmology Optic neuritis, IIH, Leber's hereditary optic neuropathy, idiopathic intracranial hypertension, optic neuropathy
  • Ocular Oncology Conjunctival, uveal, retinoblastoma, melanoma
  • Oculoplastics Thyroid eye disease, orbital tumors
  • Pediatric Ophthalmology Congenital cataract, postoperative antibiotic, inflammation, strabismus, refractive errors, pediatric neuro-ophthalmology, pediatric corneal topography
  • Retinal Diseases Retinitis pigmentosa, diabetic retinopathy, diabetic macular edema, macular hole, vitreo-macular traction, uveitis, wet and dry AMD, ocular complications of HIV/AIDS, retinopathy of prematurity
  • Telemedicine Fundus photography in the emergency department, diabetic retinopathy screening

For more information on clinical trials at Emory Eye Center or other locations, go to: http://www.clinicaltrials.gov/

Implantable Miniature Telescope (IMT)

AMD Research &Treatments

New technology helps some end-stage patients

Emory Eye Center is the first in Georgia to offer a new technology (IMT) proven to help the vision of some patients with end-stage age-related macular degeneration (AMD). The device was FDA approved in July 2010; Emory participated in the clinical trials that helped gain FDA approval. LEARN MORE >>

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