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Clinical Trials

Current clinical trials

Ocular Oncology and Pathology
Pediatric Ophthalmology

A leader in clinical research

The Emory Eye Center has for many years ranked among the top twenty eye centers in the nation by U.S. News & World Report and Ophthalmology Times.

Emory Eye Center is a recently renovated, state-of-the-art facility located in metropolitan Atlanta, Georgia, which has a population estimated at 6 million. With more than 120,000 patient encounters annually, the Emory Eye Center and its satellites is the largest, most comprehensive eye care facility in Georgia. The Emory Eye Center also staffs the Atlanta VA’s Eye Clinic with over 60,000 patient encounters and Grady Memorial Hospital (one of the largest public health systems in the United States) with almost 25,000 eye clinic patient encounters. Our 55 ophthalmologists and optometrists, most of whom are sub-specialty trained, are dedicated to quality patient care, education, teaching, and research.

We have successfully pioneered and participated in hundreds of clinical trials and studies including compassionate use, investigator-initiated, and Phase I through Phase IV studies.

We are recognized as a site where sponsors get accurate, timely and meticulous data collection; meet recruitment goals; and maintain excellent study subject retention.

Our Clinical Trials program is led by Alcides Fernandes Filho, MD, associate program director, Clinical Trials. Dr. Fernandes has participated in numerous NIH-sponsored and industry-supported clinical trials as well as in basic sciences research programs.

Site capabilities

Emory Eye Center boasts highly experienced, nationally-recognized study coordinators and leaders in ophthalmic photography. Cross-certified for numerous studies, our staff is proficient in the techniques of BCVA assessments and other visual function examinations; ophthalmic photography; anterior and posterior OCT imaging; and ultrasonography.
Research capabilities include:

  • State-of-the-art diagnostic equipment
  • Dedicated, specifically designed, multi-study certified 4-meter exam lanes featuring ETDRS and electronic visual acuity testing with specialized lighting on rheostats to meet any protocol-specific lighting requirements
  • Designated monitoring rooms with high speed internet and phone access
  • A dedicated research administration staff

Our imaging section performs external, anterior and posterior segment photography/angiography, videography, composite photography(Topcon Zeiss), anterior and posterior segment OCT and OCTA(Cirrus, Heidelberg Spectralis, Optos ), Corneal Topography (Zeiss Atlas, Oculus Pentacam, B&L Orbscan (Reichert Ocular Response Analyzer), Microperimetry, specular microscopy (Konan), corneal hysteresis Reichert ORA 3, optical biometry (Lenstar, IOL Master) and diagnostic and biometric ultrasonography (immersion and non-contact A; real-time B and UBM).

The visual field section employs Humphrey, Octopus and Goldmann perimeters. We have dedicated on-site multifocal electrophysiology testing and advanced color vision testing.

Biologic specimens are collected, centrifuged, stored (-20F and -86F freezers), packaged under CLIA accreditation and shipped by EHSO certified personnel. Investigational drugs are managed by Emory's Investigational Drug Service.

Trials and studies

Under the direction of our internationally recognized faculty, we have conducted trials and studies (pharmacologic, device, surgical treatment, registries) in:

  • Cornea: Dry eye, herpetic eye disease, keratoconus, contact lenses, cross linking, keratoprosthesis, refractive, IOL
  • Glaucoma: Adult and pediatric open angle, ocular hypertension, angle closure (medical and surgical)
  • Global Ophthalmology: Trachoma, river blindness, diabetic retinopathy, cataracts, glaucoma, Ebola
  • Low Vision/Vision Rehabilitation: Vision and functional outcomes, orientation/mobility, specially designed prisms/telescopes, implantable miniature telescope, macular degeneration/cortical plasticity
  • Neuro-Ophthalmology: Optic neuritis, IIH, Leber's hereditary optic neuropathy, idiopathic intracranial hypertension, optic neuropathy
  • Ocular Oncology and Pathology: One of very few centers in the US providing comprehensive care to patients with eye cancers including diagnosis and treatment
  • Oculoplastics: Thyroid eye disease, orbital tumors, reconstructive plastic and facial cosmetic surgery
  • Pediatric Ophthalmology: Congenital cataract, postoperative antibiotic, inflammation, strabismus, refractive errors, pediatric neuro-ophthalmology, pediatric corneal topography
  • Retinal/Vitreous Diseases: Retinitis pigmentosa, diabetic retinopathy, diabetic macular edema, macular hole, vitreo-macular traction, uveitis (anterior and posterior), wet and dry AMD, ocular complications of HIV/AIDS, retinopathy of prematurity, inherited retinal diseases
  • Telemedicine: Fundus photography in the emergency department, diabetic retinopathy screening
  • Ophthalmic Genetics: Precision medical information and testing in patients with inherited eye diseases and comprehensive care for rare and complex inherited ocular conditions

For more information on clinical trials at Emory Eye Center or other locations, go to: http://www.clinicaltrials.gov/

Closed clinical trials

Ocular Oncology and Pathology
Pediatric Ophthalmology
Vision Rehabilitation Research


Implantable Miniature Telescope (IMT)

New technology helps some end-stage patients

Emory Eye Center offesr a new technology (IMT) proven to help the vision of some patients with end-stage age-related macular degeneration (AMD).
Learn More >>

What others are saying

“It is no coincidence that Emory has been a leading
participant in virtually all of our nation’s major ophthalmology
clinical trials for over three decades. No
matter the condition being evaluated, you can always
count on Emory to recruit successfully, to conduct
the trial with reliable and timely data, and to have
a remarkable rate of study patient retention. Their
Principal Investigators are committed to the project and
their Study Coordinators are the best!”

— Academic
Ophthalmology Chair

“As a CRA for a pharmaceutical company working with
Emory PIs and coordinators for over a decade, I have
found that the Emory clinical trials department meets or
exceeds enrollment goals for a wide array of ophthalmic
study indications. The professional staff is highly knowledgeable
regarding ICH regulations and GCP guidelines.
I have confidence that Emory study staff will meet our
data deadlines, and that the PI will provide appropriate
oversight of each clinical trial.”

— Industry CRA

“Emory University clinical research unit has established
a track record for excellence with on-time recruitment,
excellent data quality and completeness, and patient

— NIH Study Chair

“As a monitor, I consider the Emory Eye Center a “High
performing site”. The site has highly experienced
and engaged investigators, coordinators and support
research staff who always produce quality and timely
data and extraordinary imaging results. The designated
Investigative Drug Service monitoring investigative
drug utilizes advanced automated wireless and alerting
systems. I am most impressed with the professionalism
that this department exhibits.”

— Industry CRA

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